Four Laws of Biology Used to Locate the Genetic Code
Short summary:
Four Laws of Biology Used to Locate the Genetic Code. By Mark White, MD Copyright Rafiki, Inc. 2008 Introduction The concept of a genetic code of protein translation was invented in the mid- twentieth century. It is now a central model of molecular biology holding that one dimension of molecular information is stored in DNA and translated into ...
Long summary:
Here is the sequence of events that led to this indefensible situation:
Observation : An atypical protein (i.e. a relatively small one) was shown to possess - and seemingly return to - a consistent conformation under a range of atypical circumstances.
Induction : Proteins can be understood to have only one stable conformation (native state) and all other conformations can be considered inherently unstable (random coil). Therefore, all proteins in the random coil state should be seen to be thermodynamically moving toward their inevitable native state (protein folding)
Deduction : Amino acid sequence determines protein structure, so molecular sequence defines molecular information.
Deduction : The genetic code is one-dimensional, and the one dimension of this code can be perfectly embodied in the standard codon table; therefore the code itself is simple, can be located within an ordinary spreadsheet, and can be completely understood in a matter of minutes.
Deduction : Since the genetic code is so simple and mostly universal, and since it is a required trait for all living cells, the genetic code has barely evolved since its appearance on earth. Furthermore, it must now be considered as an obvious and prominent inherited living trait of the last common, single-cellular ancestor of all life on earth...
Source: www.codefun.com
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